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ReproSTEM Program

Equipping CPS Teachers with Knowledge and Experience in Reproductive Tissue Engineering 

At the Laronda Lab, our scientific mission is to translate basic reproductive biology discoveries into innovative fertility preservation and hormone restoration technologies for pediatric cancer patients.
Our 4 areas of research include:


Testis organoids 

42-66% of male
childhood cancer
survivors are affected
by male factor
infertility in
adulthood- spurring
research into tools like
testicular organoids to
restore their fertility.


Engineering an ovary 

Ovarian structure is
functional - with the
extracellular matrix
providing key
biomechanical cues
that affect follicle
development and
maintenance. We
quantify architecture
of the primary
extracellular matrix
protein, collagen I,
through second
harmonic generation


Defining the ovarian microenvironment

The pubertal
transition is a key
period of dramatic
change both inside
and out of the ovary.
Histologic and gross
anatomic features
characterize ovarian


Patient derived stem-cells

Stem cells, i.e.,a
cellular population
characterized by the
ability to become any
other cell in the body,
can provide the
foundation for a cellbased hormone
replacement therapy
with the potential to
provide important
hormones, such as

ReproSTEM Sponsors


Suzanne and Michael Burns 

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