Great 2019 - Looking forward to more discoveries in 2020!

January 7, 2020

It has been a while since we have updated this site. Here are some highlights from the close of 2019! For more real-time updates follow us on Twitter!

 

Kelly Even finished her MS in Health Communication (Aug. 24, 2019) and left the Laronda Lab to be at Embryologist at Northwestern Medicine's Reproductive Infertility and Andrology Clinic (Sept. 2019). Kelly was important part of jump-starting the Laronda Lab and we wish her many successes!

 

We welcomed Grace Schwartz as a new Research Technologist II in Oct. 2019!

 

The FHPR team hosted their First Annual Patient/Family Luncheon! We launched some Lurie Children's FHPR educational videos for fertility preservation procedures and updated patients and families on the program, including ongoing research projects. We thank all who participated and appreciated patient feedback. 

 

The Artificial Ovary patent was issued to MM Laronda, A Rutz, R Shah and TK Woodruff in Nov. 2019!

 

Research Presentations:

Dr. Laronda (@mmlaronda) presented the lab's work at:

  • ART World Congress in New York

  • Chaired a session with Kyle Orwig on Regenerative Medicine and Stem Cells at the annual American Society for Reproductive Medicine Conference in Philadelphia, PA

  • International Conference on Biofabrication in Columbus, OH

  • Ovarian Club Meeting in Paris, France

  • INSERM - Workshop on 3D Bioprinting and Biofabrication in Bordeaux, France

 

Nicole Handa gave an oral presentation at American Society for Reproductive Medicine Conference in Philadelphia, PA titled: Parent Comprehension in Video-Based Education for ​Pediatric Fertility Preservation and received encouraging feedback from the audience! 

 

Dr. Courtney Harris has been representing FHPR research at several conferences:

  • Association of Women Surgeons Annual Conference in San Francisco, CA Presence of Follicles in the Discarded Processing Media in Pediatric Ovarian Tissue Cryopreservation

  • American College of Surgeons Clinical Congress in San Francisco, CA Evaluation of Tertiary Care Pediatric Hospitals for Presence of Ovarian Tissue Cryopreservation Program.

  • Society for Pediatric Urology Fall Congress in Scotsdale, AZ Establishing an Institutional Gonadal Tissue Cryopreservation Protocol for Patients with Differences of Sex Development

 

The Laronda Lab and FHPR were well-represented at the 2019 Oncofertility Consortium Conference and the Illinois Symposium on Reproductive Medicine in Chicago, IL

OC posters: (link)

  • Harris Courtney J, Lautz TB, Rowell EE. Feasibility of Laparoscopic Ovarian Tissue Cryopreservation After Open Abdominopelvic Tumor Surgery.

  • Harris Courtney J, Petukhova SP, Zhou LT, Machlin J, Duncan FE, Rowell EE , Laronda MM. Evaluation of Tissue Fragments for Presence of Follicles in the Discarded Processing Media in Pediatric Ovarian Tissue Cryopreservation.

  • Goff Shaina M, Harris CJ, Erickson LL, Bangoura A, Laronda MM, Rowell EE. Testicular Tissue Cryopreservation: Assessing Current Health Status and Evaluating the Fertility Preservation Experience.

  • Erickson Laura, Goff SM, Bangoura A, Harris C, Laronda MM, Rowell EE. Timing is Everything! Fertility Preservation Process from Patient Diagnosis Through Ovarian Tissue Cryopreservation to the Start of Treatment.

  • Bangoura Aminata, Erickson L, Goff SM, Harris C, Laronda MM, Rowell EE. Ovarian Tissue Cryopreservation in Pediatric Patients: A Post Procedure Follow-Up Assessment.

  • Kubo Hana, Even KA, Henning NFC, Laronda MM. Characterization and generation of ovarian follicle support cells

  • Henning Nathanial, Even KA, Petukhova, S, Laronda, MM. Investigating the influence of physical properties and matrisome composition of the ovarian microenvironment on folliculogenesis.

  • Petukhova Sofia, Henning N, Laronda MM. Characterizing an in situ ovarian spheroid model system of folliculogenesis using bovine ovaries.

  • Zhou L Tracy, Amargant F, Krisher RL, Roberts M, Prather RS, Harris CJ, Machlin JH, Rowell EE, Laronda MM, Duncan FE. Improving in vitro maturation of recovered cumulus oocyte complexes following processing of pediatric ovarian tissue for cryopreservation.

Dr. Erin Rowell presented evidence for removing a whole ovary in patients that opt into fertility preservation with ovarian tissue cryopreservation (link to video).

 

ISRS posters: Annual Conference (link)

  • Harris Courtney J, Petukhova SP, Zhou LT, Machlin J, Duncan FE, Rowell EE, Laronda MM. Evaluation of Tissue Fragments for Presence of Follicles in the Discarded Processing Media in Pediatric Ovarian Tissue Cryopreservation.

  • Kubo Hana, Even KA, Henning NFC, Laronda MM. Characterization and generation of ovarian follicle support cells

  • Petukhova Sofia, Henning N, Laronda MM. Characterizing an in situ ovarian spheroid model system of folliculogenesis using bovine ovaries.

  • Zhou L Tracy, Amargant F, Krisher RL, Roberts M, Prather RS, Harris CJ, Machlin JH, Rowell EE, Laronda MM, Duncan FE. Improving in vitro maturation of recovered cumulus oocyte complexes following processing of pediatric ovarian tissue for cryopreservation.

ISRS oral presentation:

 

Henning Nathanial, Even KA, Petukhova, S, Laronda, MM. Investigating the influence of physical properties and matrisome composition of the ovarian microenvironment on folliculogenesis.

 

Awards!

Dr. Courtney Harris was the Starr Resident Abstract winner at AWS 2019!

 

Publications!

Henning, N.F., LeDuc, R.D., Even, K.A. Laronda MM. Proteomic analyses of decellularized porcine ovaries identified new matrisome proteins and spatial differences across and within ovarian compartments. Sci Rep 9, 20001 (2019) doi:10.1038/s41598-019-56454-3

https://www.nature.com/articles/s41598-019-56454-3.pdf

 

Johnson E, K, Finlayson C, Finney E, L, Harris C, J, Tan S, Y, Laronda M, M, Lockart B, A, Chen D, Rowell E, E, Cheng E, Y, Yerkes E, B: Gonadal Tissue Cryopreservation for Children with Differences of Sex Development. Horm Res Paediatr 2019. doi: 10.1159/000502644

https://www.karger.com/Article/Abstract/502644#

 

 

 

Timothy B. Lautz, Courtney J. Harris, Monica M. Laronda, Laura Erickson, Erin E. Rowell. A Fertility Preservation Toolkit for Pediatric Surgeons Caring for Children with Cancer. Seminars in Pediatric Surgery. 2019 accepted

 

EE Rowell, KS Corkum, KA Even, MM Laronda. Ovarian Tissue Health After Laparoscopic Unilateral Oophorectomy: A Porcine Model for Establishing Optimized Fertility Preservation Techniques in Children. Journal of Pediatric Surgery 2019 accepted

 

 

 

 

 

 

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